Interleukin 2 – mediated Uncoupling of T Cell Receptor a / b from CD 3 Signaling

From the * Department of Microbiology and Immunology, McGill University, Montreal, Quebec, Canada H3A 2B4; the ‡ Department of Immunology, University of Toronto, and The Arthritis and Immune Disorder Research Center, Toronto, Ontario, Canada M5G 2M9; the § Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, Florida 33101; the i McGill Cancer Centre and the Departments of Biochemistry, Medicine, and Oncology, McGill University, Montreal, Quebec, Canada H3G 1Y6; and the ¶ Howard Hughes Medical Institute, University of Chicago, Chicago, Illinois 60637